Quick tips
Opt for caulk-type sealants over spray foam versions.
If foam sealing is required, go for pre-formed products, such as foam sealant tape.
For general purposes, choose acrylic, latex, or siliconized latex sealants with ultra-low VOCs (≤ 25 grams per liter).
Try to avoid silicone, polyurethane, and hybrid/modified polymer sealants.
When needing to use polyurethane or hybrid/modified polymer sealants, select versions free from phthalates.
When using silicone sealants, steer clear of those with organotin catalysts and instead choose those with titanium-based catalysts.
Avoid sealants advertised as mold or mildew-resistant unless they're essential.
If such products are used, stay away from those that have arsenic-based fungicides.
Always lean towards products that offer full ingredient transparency via Health Product Declarations (HPDs).
Ranking
Pre-compressed Polyurethane Joint Seal
Acrylic and Latex Sealants
Siliconized Latex Sealant
Acoustical Sealant
Butyl Sealant
Single-Component Silicone Sealant
Single-Component Polyurethane Foam Sealant
Hybrid/Modified Polymer Sealant
Mildew-Resistant/Sanitary Silicone Sealant
Single-Component Polyurethane Sealant
Two-Component Polyurethane Sealant